Biology:DTYMK
 Generic protein structure example |
Thymidylate kinase also known as deoxythymidylate kinase or dTMP kinase is an enzyme that in humans is encoded by the DTYMK gene.[1][2][3] and belongs to thymidylate kinase family of proteins.
References
- ↑ "Molecular cloning and expression of the human deoxythymidylate kinase gene in yeast". Nucleic Acids Res 19 (4): 823–7. May 1991. doi:10.1093/nar/19.4.823. PMID 2017365.
- ↑ "Human dTMP kinase: gene expression and enzymatic activity coinciding with cell cycle progression and cell growth". DNA Cell Biol 13 (5): 461–71. Aug 1994. doi:10.1089/dna.1994.13.461. PMID 8024690.
- ↑ "Entrez Gene: DTYMK deoxythymidylate kinase (thymidylate kinase)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1841.
Further reading
- "Phosphorylation of nucleosides and nucleoside analogs by mammalian nucleoside monophosphate kinases.". Pharmacol. Ther. 87 (2–3): 189–98. 2000. doi:10.1016/S0163-7258(00)00048-6. PMID 11008000.
- "Co-purification of thymidylate kinase and cytosolic thymidine kinase from human term placenta by affinity chromatography.". Biochim. Biophys. Acta 995 (1): 28–35. 1989. doi:10.1016/0167-4838(89)90229-X. PMID 2538159.
- "Activities of some enzymes of pyrimidine and DNA synthesis in a rat transplantable hepatoma and human primary hepatomas, in cell lines derived from these tissues, and in human fetal liver.". Cancer Res. 40 (4): 1235–9. 1980. PMID 6244089.
- "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1–2): 171–4. 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1–2): 149–56. 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Structures of human thymidylate kinase in complex with prodrugs: implications for the structure-based design of novel compounds.". Biochemistry 42 (9): 2568–77. 2003. doi:10.1021/bi027302t. PMID 12614151.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
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