Biology:Deacetylipecoside synthase

From HandWiki
deacetylipecoside synthase
Identifiers
EC number4.3.3.4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The enzyme deacetylipecoside synthase (EC 4.3.3.4) catalyzes the chemical reaction

deacetylipecoside + H2O [math]\displaystyle{ \rightleftharpoons }[/math] dopamine + secologanin

This enzyme belongs to the family of lyases, specifically amine lyases, which cleave carbon-nitrogen bonds. The systematic name of this enzyme class is deacetylipecoside dopamine-lyase (secologanin-forming). This enzyme is also called deacetylipecoside dopamine-lyase. It participates in indole and ipecac alkaloid biosynthesis.

References

  • "Enzymatic condensation of dopamine and secologanin by cell-free extracts of Alangium lamarckii". Phytochemistry 45 (3): 477–484. 1997. doi:10.1016/S0031-9422(96)00828-X.