Biology:Diverticular disease
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Diverticular disease is when problems occur due to diverticulosis, a condition defined by the presence of pouches in the wall of the large intestine (diverticula).[1] This includes diverticula becoming inflamed (diverticulitis) or bleeding.[2] Colonic perforation due to diverticular disease may be classified using the Hinchey Classification.[3]
Signs and symptoms
The signs and symptoms of diverticulitis are as follows:[4]
- Nausea and vomiting.
- Fever
- Abdominal tenderness
- Constipation
- Diarrhea
- Pain, may be persistent for days. Pain is usually most felt at the right side of the abdomen, by people of Asian descent.[5]
Causes
The causes of Diverticular disease can be classified into:
- Diverticula: This occurs when the weak tissues around the colon tear under pressure. Pouches of marble size protrude through the colon wall as a result of this breakaway.
- Diverticulitis: This is a direct result of the tear in diverticula, causing inflammation.
Risk Factors
Several factors contribute to the increased risk factor for diverticulitis:[6]
A diet that is low in fibre and high in fat may increase the risk of developing diverticular disease
Other factors are obesity, lack of exercise or physical inactivity, smoking, genetic disorders.
Diagnosis
Tenderness can be noticed over the inflamed tissues and an elevation of white blood cell counts is also observed after an examination by a physician. This inflammation is typically in the lower left abdomen. CT scan is the most appropriate method used for diagnosis.[7]
References
- ↑ "Clinical manifestations and diagnosis of colonic diverticular disease". Literature review. http://www.uptodate.com/contents/clinical-manifestations-and-diagnosis-of-colonic-diverticular-disease.
- ↑ "Diverticular Disease". September 2013. http://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/diverticular-disease/Pages/facts.aspx. Retrieved 12 June 2016.
- ↑ Klarenbeek, Bastiaan R.; de Korte, Niels; van der Peet, Donald L.; Cuesta, Miguel A. (17 September 2011). "Review of current classifications for diverticular disease and a translation into clinical practice". International Journal of Colorectal Disease 27 (2): 207–214. doi:10.1007/s00384-011-1314-5. PMID 21928041.
- ↑ "Diverticulitis". https://www.mayoclinic.org/diseases-conditions/diverticulitis/symptoms-causes/syc-20371758.
- ↑ "Diverticulitis". https://www.mayoclinic.org/diseases-conditions/diverticulitis/symptoms-causes/syc-20371758.
- ↑ "Diverticular Disease". https://www.lecturio.com/concepts/diverticular-disease/.
- ↑ "Diverticular disease of the colon". August 2010. https://www.health.harvard.edu/diseases-and-conditions/diverticular-disease-of-the-colon.
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