Biology:EmrB-Lactobacillus RNA motif
| emrB-Lactobacillus | |
|---|---|
 Consensus secondary structure and sequence conservation of emrB-Lactobacillus RNA | |
| Identifiers | |
| Symbol | emrB-Lactobacillus |
| Rfam | RF02971 |
| Other data | |
| RNA type | Gene; sRNA |
| SO | 0001263 |
| PDB structures | PDBe |
The emrB-Lactobacillus RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] emrB-Lactobacillus motifs are found in bacteria of the genus Lactobacillus.
emrB-Lactobacillus RNAs are generally located in the 5′ untranslated regions of genes that encode EmrB, a kind of transporter. This fact suggests that the RNAs function as cis-regulatory elements. However, two factors call this conclusion into question. First, emrB-Lactobacillus RNAs are also located nearby to their upstream genes. Regulation of an upstream gene is unusual in bacteria. Second, some emrB-Lactobacillus RNAs are located nearby to transposase genes. The presence of these genes could suggest that emrB-Lactobacillus RNAs have a function related to transposons, although it is also consistent with the view that the apparent transposons have merely replicated nearby to the emrB-Lactobacillus RNAs by coincidence, and that there is no functional relationship between the two entities. Thus, it is unknown whether emrB-Lactobacillus RNAs function as cis-regulatory RNAs or as small RNAs.
References
- ↑ "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. October 2017. doi:10.1093/nar/gkx699. PMID 28977401.
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