Biology:Expressome
From HandWiki
Expressome may refer to:
- A supramolecular complex consisting of RNA polymerase and a trailing ribosome linked by a shared mRNA. The expressome complex mediates a mechanism of gene expression regulation termed transcription-translation coupling.[1][2][3]
- The whole set of gene expression in a cell, tissue, organ, organisms, and species. Expressome is a slightly larger concept than transcriptome. The transcriptome is the set of transcripts, while expressome includes transcripts, proteins and other ligands (abundance or concentration).
See also
- Bioinformatics
- DNA microarray
- Gel electrophoresis
- Mass spectrometry
- Protein sequencing
- Systems biology
- Expressomics
- List of omics topics in biology
External links
References
- ↑ Kohler, R.; Mooney, R. A.; Mills, D. J.; Landick, R.; Cramer, P. (2017). "Architecture of a transcribing-translating expressome.". Science 356 (6334): 194–197. doi:10.1126/science.aal3059. PMID 28408604. Bibcode: 2017Sci...356..194K.
- ↑ Webster, M. W.; Takacs, M.; Zhu, C.; Vidmar, V.; Eduljee, A.; Abdelkareem, M.; Weixlbaumer, A. (2020). "Structural basis of transcription-translation coupling and collision in bacteria.". Science 369 (6509): 1355–1359. doi:10.1126/science.abb5036. PMID 32820062. Bibcode: 2020Sci...369.1355W.
- ↑ O'Reilly, F. J.; Xue, L.; Graziadei, A.; Sinn, L.; Lenz, S.; Tegunov, D.; Blötz, C.; Singh, N. et al. (2020). "In-cell architecture of an actively transcribing-translating expressome.". Science 369 (6503): 554–557. doi:10.1126/science.abb3758. PMID 32732422. Bibcode: 2020Sci...369..554O.
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