Biology:FAF1

From HandWiki
A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

FAS-associated factor 1 is a protein that in humans is encoded by the FAF1 gene.[1][2]

Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain.[2]

References

  1. "Identification and characterization of human Fas associated factor 1, hFAF1". Biochem Biophys Res Commun 262 (2): 388–94. Oct 1999. doi:10.1006/bbrc.1999.1217. PMID 10462485. 
  2. 2.0 2.1 "Entrez Gene: FAF1 Fas (TNFRSF6) associated factor 1". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11124. 

Further reading