Biology:FGD2
From HandWiki
 Generic protein structure example |
FYVE, RhoGEF and PH domain-containing protein 2 (FGD2), also known as zinc finger FYVE domain-containing protein 4 (ZFYVE4), is a protein that in humans is encoded by the FGD2 gene.[1]
It is a member of the FYVE, RhoGEF and PH domain containing family.
References
Further reading
- "NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway.". J. Biol. Chem. 277 (50): 48043–50. 2002. doi:10.1074/jbc.M205324200. PMID 12376548.
- "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805–11. 2003. doi:10.1038/nature02055. PMID 14574404. Bibcode: 2003Natur.425..805M.
- "Characterization of long cDNA clones from human adult spleen.". DNA Res. 7 (6): 357–66. 2000. doi:10.1093/dnares/7.6.357. PMID 11214971.
- "Isolation, characterization, and mapping of the mouse and human Fgd2 genes, faciogenital dysplasia (FGD1; Aarskog syndrome) gene homologues.". Genomics 60 (1): 57–66. 1999. doi:10.1006/geno.1999.5903. PMID 10458911.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.". J. Neurosci. 22 (1): 156–66. 2002. doi:10.1523/JNEUROSCI.22-01-00156.2002. PMID 11756498.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2002. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR).". Cytokine Growth Factor Rev. 14 (3–4): 225–39. 2003. doi:10.1016/S1359-6101(03)00018-2. PMID 12787561.
- "FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles.". J. Biol. Chem. 283 (49): 34002–12. 2008. doi:10.1074/jbc.M803957200. PMID 18838382.
- "Mutations in FGD4 encoding the Rho GDP/GTP exchange factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4H.". Am. J. Hum. Genet. 81 (1): 1–16. 2007. doi:10.1086/518428. PMID 17564959.
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