Biology:Ferm and pdz domain containing 4

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A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example


FERM and PDZ domain containing 4 is a protein that in humans is encoded by the FRMPD4 gene. [1]

Function

This gene encodes a multi-domain (WW, PDZ, FERM) containing protein. Through its interaction with other proteins (such as PSD-95), it functions as a positive regulator of dendritic spine morphogenesis and density, and is required for the maintenance of excitatory synaptic transmission.

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.