Biology:Gadusol
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Gadusol is a secondary metabolite and natural sunscreen produced by various organisms, including marine vertebrates and invertebrates, amphibians, reptiles, and birds.[1][2]
It functions by absorbing ultraviolet radiation through its conjugated ring structure, blocking it from damaging biomolecules.[3] Gladusol is closely related to the mycosporine-like amino acid family[2], a group of metabolites primarily produced by organisms in high-sunlight environments that absorb UV radiation. Structurally, gadusol is a substituted cyclohexenone.
References
- ↑ Rice, Marlen C.; Little, Jordan H.; Forrister, Dale L.; Machado, Julane; Clark, Nathan L.; Gagnon, James A. (2023-08-07). "Gadusol is a maternally provided sunscreen that protects fish embryos from DNA damage". Current Biology: CB 33 (15): 3229–3237.e4. doi:10.1016/j.cub.2023.06.012. ISSN 1879-0445. PMID 37369210. Bibcode: 2023CBio...33E3229R.
- ↑ 2.0 2.1 Osborn, Andrew R; Almabruk, Khaled H; Holzwarth, Garrett; Asamizu, Shumpei; LaDu, Jane; Kean, Kelsey M; Karplus, P Andrew; Tanguay, Robert L et al. (2015-05-12). van der Donk, Wilfred A. ed. "De novo synthesis of a sunscreen compound in vertebrates". eLife 4. doi:10.7554/eLife.05919. ISSN 2050-084X. PMID 25965179. Bibcode: 2015eLife...405919O.
- ↑ Carvalho, P. Gigena; Naveira, R. Isla; Granone, L. I.; Mendive, C. B.; Massa, A. E.; Churio, M. S. (2023-10-01). "A comparative review of natural and synthetic UV filters: Gadusol and benzophenone-3 as representative examples". Environmental Advances 13. doi:10.1016/j.envadv.2023.100404. ISSN 2666-7657. Bibcode: 2023EnvAd..1300404C. https://www.sciencedirect.com/science/article/pii/S2666765723000625.
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