Biology:Gelatinase biosynthesis-activating pheromone

From HandWiki
Gelatinase biosynthesis activating pheromone
Identifiers
OrganismEnterococcus faecalis
SymbolfsrD
UniProtG8ADN7

Gelatinase biosynthesis-activating pheromone abbreviated as GBAP is a cyclic peptide produced by pathogenic bacteria such as Enterococcus faecalis.[1] GAP is part of the quorum sensing system of certain bacteria where it positively regulates the expression of gelatinase and serine proteases that are under the control of the gelE-sprE operon.[2]

GBAP is an 11-amino-acid-residue cyclic peptide containing a lactone linkage between the C-terminal carboxylic acid group and a serine side chain hydroxyl group.[2]

References