Biology:Growing teeth
From HandWiki
Growing teeth is a bioengineering technology with the ultimate goal to create new full molars in a person or an animal.
Chronology
- 2002 – British scientists have learned how to grow almost whole, but feeble teeth from single cells.
- 2007 – Japanese scientists have bred mice almost full new teeth, but without a root.
- 2009 – from the stem cells were grown full teeth in mice, and even managed to grow a tooth root, previously it was not possible, but there is a problem, it is that grown teeth were slightly less "native" teeth.[1]
- 2013 - Chinese scientists grow human teeth in mice using stem cells taken from human urine.[2]
- 2015 - Growing New Teeth in the Mouth Using Stem-Cell Dental Implants [3]
- 2018 - Protein disorder–order interplay to guide the growth of hierarchical mineralized structures.[4]
Methods
- Outer – the tooth is grown separately and implanted in the patient.
- Inner – the tooth is grown directly into the patient's mouth.
Regenerative Research
- 2012 – Indian researchers found a way to cure and regenerate an infected root canal through stem cell activation. This replaces the old method of removing the tooth nerve.[5]
- 2013 - Swiss researchers regenerate tooth enamel of early cavities using a peptide-based biomaterial.[6]
References
- ↑ Normile, Dennis (3 August 2009). "Researchers Grow New Teeth in Mice". Science. https://www.science.org/content/article/researchers-grow-new-teeth-mice.
- ↑ "Stem cells extracted from urine used to 'grow teeth' - NHS". http://www.nhs.uk/news/2013/07july/pages/stem-cells-extracted-from-urine-used-to-grow-teeth.aspx.
- ↑ "Growing New Teeth in the Mouth Using Stem-Cell Dental Implants". PreScouter. 26 July 2015. https://www.prescouter.com/2015/07/growing-new-teeth-in-the-mouth-using-stem-cell-dental-implants/.
- ↑ Elsharkawy, Sherif; Al-Jawad, Maisoon; Pantano, Maria F.; Tejeda-Montes, Esther; Mehta, Khushbu; Jamal, Hasan; Agarwal, Shweta; Shuturminska, Kseniya et al. (1 June 2018). "Protein disorder–order interplay to guide the growth of hierarchical mineralized structures". Nature Communications 9 (1): 2145. doi:10.1038/s41467-018-04319-0. PMID 29858566. Bibcode: 2018NatCo...9.2145E.
- ↑ Dutt, Anuradha (September 2013). "Breakthrough dentistry". The Hindu. http://www.thehindu.com/sci-tech/health/breakthrough-dentistry/article5076022.ece.
- ↑ Brunton, P. A.; Davies, R. P. W.; Burke, J. L.; Smith, A.; Aggeli, A.; Brookes, S. J.; Kirkham, J. (August 2013). "Treatment of early caries lesions using biomimetic self-assembling peptides – a clinical safety trial". British Dental Journal 215 (4): E6. doi:10.1038/sj.bdj.2013.741. PMID 23969679.
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