Biology:IGHD

Short description: Gene in the species Homo sapiens

Generic protein structure example

Ig delta chain C region is a protein that in humans is encoded by the IGHD gene.

Further reading

• "Structural and functional properties of mouse-human chimeric IgD.". Hum. Antibodies Hybridomas 3 (2): 65–74. 1992. doi:10.3233/HAB-1992-3202. PMID 1633267. 
• "Cell autonomous expression of IgD is not essential for the maturation of conventional B cells.". Int. Immunol. 3 (12): 1367–71. 1992. doi:10.1093/intimm/3.12.1367. PMID 1838007. 
• "Complete amino acid sequence of the Fc region of a human delta chain". Proc. Natl. Acad. Sci. U.S.A. 78 (2): 785–9. 1981. doi:10.1073/pnas.78.2.785. PMID 6785754. Bibcode: 1981PNAS...78..785S. 
• "Primary structure of the Fc region of human immunoglobulin D: implications for evolutionary origin and biological function". Proc. Natl. Acad. Sci. U.S.A. 78 (1): 504–8. 1981. doi:10.1073/pnas.78.1.504. PMID 6787589. Bibcode: 1981PNAS...78..504L. 
• "Amino acid sequence of the first constant region domain and the hinge region of the delta heavy chain of human IgD". Proc. Natl. Acad. Sci. U.S.A. 78 (10): 6168–72. 1982. doi:10.1073/pnas.78.10.6168. PMID 6947220. 
• "Amino acid sequence and location of the three glycopeptides in the Fc region of human immunoglobulin D". Biochem. Biophys. Res. Commun. 97 (2): 635–41. 1981. doi:10.1016/0006-291X(80)90311-3. PMID 7008791. 
• "Amino acid sequence of galactosamine-containing glycopeptides in the hinge region of a human immunoglobulin D". Biochem. Biophys. Res. Commun. 105 (3): 1066–71. 1982. doi:10.1016/0006-291X(82)91078-6. PMID 7092891. 
• "Immunoglobulin D (IgD)-deficient mice reveal an auxiliary receptor function for IgD in antigen-mediated recruitment of B cells". J. Exp. Med. 177 (1): 45–55. 1993. doi:10.1084/jem.177.1.45. PMID 8418208. 
• "Molecular cloning, expression and chromosomal localization of a human gene encoding a 33 kDa putative metallopeptidase (PRSM1)". Gene 174 (1): 135–43. 1996. doi:10.1016/0378-1119(96)00510-0. PMID 8863740. 
• "Role of surface IgM and IgD on survival of the cells from B-cell chronic lymphocytic leukemia". Blood 99 (6): 2277–8. 2002. doi:10.1182/blood-2001-11-0126. PMID 11902141. 
• "The role of constant region carbohydrate in the assembly and secretion of human IgD and IgA1". J. Biol. Chem. 277 (32): 29005–11. 2002. doi:10.1074/jbc.M203258200. PMID 12023968. 
• "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M. 
• "A high-molecular-weight complex of membrane proteins BAP29/BAP31 is involved in the retention of membrane-bound IgD in the endoplasmic reticulum". Proc. Natl. Acad. Sci. U.S.A. 100 (17): 9861–6. 2003. doi:10.1073/pnas.1633363100. PMID 12886015. Bibcode: 2003PNAS..100.9861S. 
• "Human Plasma N-Glycoproteome Analysis by Immunoaffinity Subtraction, Hydrazide Chemistry, and Mass Spectrometry". J. Proteome Res. 4 (6): 2070–80. 2006. doi:10.1021/pr0502065. PMID 16335952. 
• "Reconsidering the human immunoglobulin heavy-chain locus: 1. An evaluation of the expressed human IGHD gene repertoire". Immunogenetics 57 (12): 917–25. 2006. doi:10.1007/s00251-005-0062-5. PMID 16402215. 
• "Use of IGHJ and IGHD gene mutations in analysis of immunoglobulin sequences for the prognosis of chronic lymphocytic leukemia". Leuk. Res. 31 (9): 1247–52. 2007. doi:10.1016/j.leukres.2006.10.013. PMID 17169423. 
• "Characterization of the IgD binding site of encapsulated Haemophilus influenzae serotype b". J. Immunol. 178 (10): 6316–9. 2007. doi:10.4049/jimmunol.178.10.6316. PMID 17475860.