Biology:IMES-5 RNA motif
From HandWiki
| IMES-5 | |
|---|---|
 Consensus secondary structure and sequence conservation of IMES-5 RNA | |
| Identifiers | |
| Symbol | IMES-5 |
| Rfam | RF02995 |
| Other data | |
| RNA type | Gene; sRNA |
| SO | 0001263 |
| PDB structures | PDBe |
The IMES-5 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] These RNAs are present in environmental sequences, and have not yet (as of 2018) been identified in a classified organism.
It is ambiguous whether IMES-5 RNAs function as cis-regulatory elements or whether they operate in trans. The RNAs are often found upstream of genes that encode an acyl-tRNA synthetase that is specific for tryptophan. However, this association is not consistent to declare a cis-regulatory function for the RNA, and so it might function as a small RNA.
References
- ↑ "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. October 2017. doi:10.1093/nar/gkx699. PMID 28977401.
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