Biology:KRT33B
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 Generic protein structure example |
Keratin, type I cuticular Ha3-II is a protein that in humans is encoded by the KRT33B gene.[1][2][3]
The protein encoded by this gene is a member of the keratin gene family. It is one of the type I hair keratin genes which are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II hair keratin to form hair and nails. There are two isoforms of this protein, encoded by two separate genes, KRTHA3A and KRTHA3B.[3]
References
- ↑ "A novel human type I hair keratin gene: evidence for two keratin hHa3 isoforms". Mol Biol Rep 20 (3): 155–61. Nov 1995. doi:10.1007/BF00990548. PMID 7565656.
- ↑ "New consensus nomenclature for mammalian keratins". J Cell Biol 174 (2): 169–74. Jul 2006. doi:10.1083/jcb.200603161. PMID 16831889.
- ↑ 3.0 3.1 "Entrez Gene: KRT33B keratin 33B". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3884.
Further reading
- "Human hair keratins.". J. Invest. Dermatol. 101 (1 Suppl): 56S–59S. 1993. doi:10.1111/1523-1747.ep12362635. PMID 7686952.
- "Characterization of a 190-kilobase pair domain of human type I hair keratin genes.". J. Biol. Chem. 273 (41): 26683–91. 1998. doi:10.1074/jbc.273.41.26683. PMID 9756910.
- "The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle.". J. Biol. Chem. 274 (28): 19874–84. 1999. doi:10.1074/jbc.274.28.19874. PMID 10391933.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "The human plasma proteome: a nonredundant list developed by combination of four separate sources.". Mol. Cell. Proteomics 3 (4): 311–26. 2004. doi:10.1074/mcp.M300127-MCP200. PMID 14718574.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3 (1): 89. 2007. doi:10.1038/msb4100134. PMID 17353931.
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