Biology:LHFP
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Lipoma HMGIC fusion partner is a protein that in humans is encoded by the LHFP gene.[1][2]
This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. This gene is fused to a high-mobility group gene in a translocation-associated lipoma. Mutations in another LHFP-like gene (LHFPL1, LHFPL2) result in deafness in humans and mice. Alternatively spliced transcript variants have been found; however, their full-length nature is not known.[2]
References
- ↑ "LHFP, a novel translocation partner gene of HMGIC in a lipoma, is a member of a new family of LHFP-like genes". Genomics 57 (3): 438–41. Aug 1999. doi:10.1006/geno.1999.5778. PMID 10329012.
- ↑ 2.0 2.1 "Entrez Gene: LHFP lipoma HMGIC fusion partner". https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=10186.
Further reading
- "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. 2006. doi:10.1101/gr.4039406. PMID 16344560.
- "A missense mutation in the previously undescribed gene Tmhs underlies deafness in hurry-scurry (hscy) mice". Proc. Natl. Acad. Sci. U.S.A. 102 (22): 7894–9. 2005. doi:10.1073/pnas.0500760102. PMID 15905332. Bibcode: 2005PNAS..102.7894L.
- "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "The DNA sequence and analysis of human chromosome 13". Nature 428 (6982): 522–8. 2004. doi:10.1038/nature02379. PMID 15057823. Bibcode: 2004Natur.428..522D.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
External links
- LHFP human gene location in the UCSC Genome Browser.
- LHFP human gene details in the UCSC Genome Browser.
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