Biology:LMOD3

From HandWiki
Short description: Protein-coding gene in humans


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Leiomodin-3 is a protein that in humans is encoded by the LMOD3 gene.[1][2]

Clinical significance

Dysfunction is associated with thin filament disorganisation and nemaline myopathy.[3]

References

  1. "Entrez Gene: LMOD3 leiomodin 3 (fetal)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56203. 
  2. "The evolution of compositionally and functionally distinct actin filaments". Journal of Cell Science 128 (11): 2009–19. June 2015. doi:10.1242/jcs.165563. PMID 25788699. 
  3. "Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy". The Journal of Clinical Investigation 124 (11): 4693–708. November 2014. doi:10.1172/JCI75199. PMID 25250574. 

Further reading