Biology:Latarcin

From HandWiki
Latarcin
Identifiers
SymbolLatarcin
PfamPF10279
InterProIPR018802
OPM superfamily259
OPM protein2pco

Latarcins are short antimicrobial peptides from the venom of the spider Lachesana tarabaevi.[1] Latarcins adopt an amphipathic alpha-helical structure in the plasma membrane. Possible pharmacological applications for latarcins include antimicrobial and anticancer treatments.[2]

References

  1. "Latarcins, antimicrobial and cytolytic peptides from the venom of the spider Lachesana tarabaevi (Zodariidae) that exemplify biomolecular diversity". J. Biol. Chem. 281 (30): 20983–92. July 2006. doi:10.1074/jbc.M602168200. PMID 16735513. 
  2. Dubovskii, P.V.; Vassilevski, A.A.; Kozlov, S.A.; Feofanov, A.V.; Grishin, E.V.; Efremov, R.G. (2015). "Latarcins: versatile spider venom peptides". Cellular and Molecular Life Sciences 72 (23): 4501–4522. doi:10.1007/s00018-015-2016-x. PMID 26286896. 
This article incorporates text from the public domain Pfam and InterPro: IPR018802