Biology:MBNL2
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Muscleblind-like protein 2 is a protein that in humans is encoded by the MBNL2 gene.[1][2]
This gene encodes a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein. Drosophila muscleblind is a gene required for photoreceptor differentiation. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined.[2]
References
- ↑ "Three proteins, MBNL, MBLL and MBXL, co-localize in vivo with nuclear foci of expanded-repeat transcripts in DM1 and DM2 cells". Hum Mol Genet 11 (7): 805–14. Apr 2002. doi:10.1093/hmg/11.7.805. PMID 11929853.
- ↑ 2.0 2.1 "Entrez Gene: MBNL2 muscleblind-like 2 (Drosophila)". https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=10150.
Further reading
- Adereth Y; Dammai V; Kose N et al. (2006). "RNA-dependent integrin α3 protein localization regulated by the Muscleblind-like protein MLP1". Nat. Cell Biol. 7 (12): 1240–7. doi:10.1038/ncb1335. PMID 16273094.
- Gerhard DS; Wagner L; Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Ho TH; Charlet-B N; Poulos MG et al. (2005). "Muscleblind proteins regulate alternative splicing". EMBO J. 23 (15): 3103–12. doi:10.1038/sj.emboj.7600300. PMID 15257297.
- Dunham A; Matthews LH; Burton J et al. (2004). "The DNA sequence and analysis of human chromosome 13". Nature 428 (6982): 522–8. doi:10.1038/nature02379. PMID 15057823. Bibcode: 2004Natur.428..522D.
- Strausberg RL; Feingold EA; Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- Christian SL; McDonough J; Liu Cy CY et al. (2002). "An evaluation of the assembly of an approximately 15-Mb region on human chromosome 13q32-q33 linked to bipolar disorder and schizophrenia". Genomics 79 (5): 635–56. doi:10.1006/geno.2002.6765. PMID 11991713.
External links
- MBNL2 human gene location in the UCSC Genome Browser.
- MBNL2 human gene details in the UCSC Genome Browser.
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