Biology:ME2 (gene)

NAD-dependent malic enzyme, mitochondrial is a protein that in humans is encoded by the ME2 gene.^[1]^[2] This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene.^[2]

References

↑ "Human NAD(+)-dependent mitochondrial malic enzyme. cDNA cloning, primary structure, and expression in Escherichia coli". J Biol Chem 266 (5): 3016–21. Mar 1991. doi:10.1016/S0021-9258(18)49948-6. PMID 1993674.
↑ ^2.0 ^2.1 "Entrez Gene: ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4200.

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