Biology:MFSD1

From HandWiki
Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Major facilitator superfamily domain containing 1 (MFSD1, SMAP) is a protein belonging to the MFS Pfam clan.[1] It is an Atypical solute carrier.[2]

It belongs to the major facilitator superfamily MFS Pfam Clan. MFSD1 has been identified in neuronal plasma membranes [2] and lysosomes.[3][4]

HGNC:25874

MFSD1 belongs to AMTF6.[5]

References

  1. "Classification Systems of Secondary Active Transporters". Trends in Pharmacological Sciences 38 (3): 305–315. March 2017. doi:10.1016/j.tips.2016.11.008. PMID 27939446. 
  2. 2.0 2.1 "The Novel Membrane-Bound Proteins MFSD1 and MFSD3 are Putative SLC Transporters Affected by Altered Nutrient Intake". Journal of Molecular Neuroscience 61 (2): 199–214. February 2017. doi:10.1007/s12031-016-0867-8. PMID 27981419. 
  3. "An extended proteome map of the lysosomal membrane reveals novel potential transporters". Molecular & Cellular Proteomics 12 (6): 1572–88. June 2013. doi:10.1074/mcp.M112.021980. PMID 23436907. 
  4. "Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways". Human Molecular Genetics 20 (19): 3852–66. October 2011. doi:10.1093/hmg/ddr306. PMID 21752829. 
  5. "Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression" (in en). Open Biology 7 (9): 170142. September 2017. doi:10.1098/rsob.170142. PMID 28878041.