Biology:MIMT1
From HandWiki
Short description: Non-coding RNA
In molecular biology, MER1 repeat containing imprinted transcript 1 (non-protein coding), also known as MIMT1 is a long non-coding RNA. It is an imprinted gene, which is paternally expressed.[1] Deletion of this gene is lethal in cattle, causing still births and abortions. It is lethal in 85% of individuals with the deletion, it is thought that incomplete silencing of maternally imprinted alleles allows some individuals with the deletion to survive.[2]
See also
- Long noncoding RNA
References
- ↑ Kim, J.; Bergmann, A.; Choo, J. H.; Stubbs, L. (2007). "Genomic organization and imprinting of the Peg3 domain in bovine". Genomics 90 (1): 85–92. doi:10.1016/j.ygeno.2007.03.012. PMID 17509818.
- ↑ Flisikowski, K.; Venhoranta, H.; Nowacka-Woszuk, J.; McKay, S. D.; Flyckt, A.; Taponen, J.; Schnabel, R.; Schwarzenbacher, H. et al. (2010). Roberts, Roland G.. ed. "A Novel Mutation in the Maternally Imprinted PEG3 Domain Results in a Loss of MIMT1 Expression and Causes Abortions and Stillbirths in Cattle (Bos taurus)". PLOS ONE 5 (11): e15116. doi:10.1371/journal.pone.0015116. PMID 21152099. Bibcode: 2010PLoSO...515116F.
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