Biology:MIS12

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A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Protein MIS12 homolog is a protein that in humans is encoded by the MIS12 gene.[1][2][3]


Interactions

MIS12 has been shown to interact with NSL1,[4] ZWINT,[4][5] CASC5,[4][5] Polyamine-modulated factor 1,[4][5] NDC80,[4][5] DSN1[4][5] and CBX5.[4]

References

  1. "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res 11 (3): 422–35. Mar 2001. doi:10.1101/gr.GR1547R. PMID 11230166. 
  2. "Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway". J Cell Biol 160 (1): 25–39. Jan 2003. doi:10.1083/jcb.200210005. PMID 12515822. 
  3. "Entrez Gene: MIS12 MIS12, MIND kinetochore complex component, homolog (yeast)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79003. 
  4. 4.0 4.1 4.2 4.3 4.4 4.5 4.6 Obuse, Chikashi; Iwasaki Osamu; Kiyomitsu Tomomi; Goshima Gohta; Toyoda Yusuke; Yanagida Mitsuhiro (Nov 2004). "A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1". Nat. Cell Biol. (England) 6 (11): 1135–41. doi:10.1038/ncb1187. ISSN 1465-7392. PMID 15502821. 
  5. 5.0 5.1 5.2 5.3 5.4 Cheeseman, Iain M; Niessen Sherry; Anderson Scott; Hyndman Francie; Yates John R; Oegema Karen; Desai Arshad (Sep 2004). "A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension". Genes Dev. (United States) 18 (18): 2255–68. doi:10.1101/gad.1234104. ISSN 0890-9369. PMID 15371340. 

Further reading