Biology:MLLT3
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Protein AF-9 is a protein that in humans is encoded by the MLLT3 gene.[1][2][3]
Interactions
MLLT3 has been shown to interact with BCOR.[4]
References
- ↑ "Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs". Proc Natl Acad Sci U S A 90 (10): 4631–5. Jul 1993. doi:10.1073/pnas.90.10.4631. PMID 8506309. Bibcode: 1993PNAS...90.4631N.
- ↑ "MLLT3 gene on 9p22 involved in t(9;11) leukemia encodes a serine/proline rich protein homologous to MLLT1 on 19p13". Oncogene 8 (11): 3085–92. Nov 1993. PMID 8414510.
- ↑ "Entrez Gene: MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3". https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=4300.
- ↑ Srinivasan, R Sathish; de Erkenez Andrea C; Hemenway Charles S (May 2003). "The mixed lineage leukemia fusion partner AF9 binds specific isoforms of the BCL-6 corepressor". Oncogene 22 (22): 3395–406. doi:10.1038/sj.onc.1206361. ISSN 0950-9232. PMID 12776190.
Further reading
- "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1–2): 171–4. 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1–2): 149–56. 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- "BCoR, a novel corepressor involved in BCL-6 repression.". Genes Dev. 14 (14): 1810–23. 2000. doi:10.1101/gad.14.14.1810. PMID 10898795.
- "The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3.". Oncogene 20 (4): 411–9. 2001. doi:10.1038/sj.onc.1204108. PMID 11313972.
- "The polycomb protein MPc3 interacts with AF9, an MLL fusion partner in t(9;11)(p22;q23) acute leukemias.". Oncogene 20 (29): 3798–805. 2001. doi:10.1038/sj.onc.1204478. PMID 11439343.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "The mixed lineage leukemia fusion partner AF9 binds specific isoforms of the BCL-6 corepressor.". Oncogene 22 (22): 3395–406. 2003. doi:10.1038/sj.onc.1206361. PMID 12776190.
- "MLL fusion partners AF4 and AF9 interact at subnuclear foci.". Leukemia 18 (1): 92–102. 2004. doi:10.1038/sj.leu.2403200. PMID 14603337.
- "Identification of two MLL-MLLT3 (alias MLL-AF9) chimeric transcripts in the MOLM-13 cell line.". Cancer Genet. Cytogenet. 154 (1): 96–7. 2004. doi:10.1016/j.cancergencyto.2004.01.029. PMID 15381384.
- "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
- "Down-regulation of MLL-AF9, MLL and MYC expression is not obligatory for monocyte-macrophage maturation in AML-M5 cell lines carrying t(9;11)(p22;q23).". Oncol. Rep. 15 (1): 207–11. 2006. doi:10.3892/or.15.1.207. PMID 16328057.
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