Biology:MPP2

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A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

MAGUK p55 subfamily member 2 is a protein that in humans is encoded by the MPP2 gene.[1][2]

Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction.[2]

References

  1. "A gene (DLG2) located at 17q12-q21 encodes a new homologue of the Drosophila tumor suppressor dIg-A". Genomics 28 (1): 25–31. Dec 1995. doi:10.1006/geno.1995.1101. PMID 7590743. 
  2. 2.0 2.1 "Entrez Gene: MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4355. 

Further reading