Biology:MicroVacuum
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MicroVacuum Ltd. is a Hungarian biotechnology company based in Budapest. MicroVacuum is a global supplier of label-free biosensor systems for the life-science research market to provide real-time, label free detection and characterization of surface adsorption.[1]
MicroVacuum develops, manufactures, and markets the OWLS label-free, real-time biosensor system based on the grating coupler waveguide technology. The OW optical sensors and OWLS analytical system allow the determination of the affinity and kinetics of a wide variety of molecular interactions in real time, without the need for a molecular tag or label.
Applications include protein quantification, classification of protein-protein and protein-DNA interactions, drug screening, and immunosensing.
The main biosensing applications of the OWLS technology are as follows:
- Adsorption of proteins at surfaces
- Immunosensing
- Drug screening
- Ligand / receptor binding
- Kinetics of adhesion, growth and spreading of living cells
- Protein - lipid bilayer interactions
- Protein - DNA interactions
- Molecular self-assembly & nanoscience
- Analysis of association and dissociation kinetics
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