Biology:Mothers against decapentaplegic
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Short description: Protein
Mothers against decapentaplegic is a protein from the SMAD family that was discovered in Drosophila. During Drosophila research, it was found that a mutation in the gene in the mother repressed the gene decapentaplegic in the embryo. The phrase "Mothers against" was added as a humorous take-off on organizations opposing various issues e.g. Mothers Against Drunk Driving (MADD); and based on a tradition of such unusual naming within the gene research community.[1][2][3]
Several human homologues are known:
- Mothers against decapentaplegic homolog 1
- Mothers against decapentaplegic homolog 2
- Mothers against decapentaplegic homolog 3
- Mothers against decapentaplegic homolog 4
- Mothers against decapentaplegic homolog 5
- Mothers against decapentaplegic homolog 6
- Mothers against decapentaplegic homolog 7
- Mothers against decapentaplegic homolog 9
References
- ↑ White, Michael (September 26, 2014). "Sonic Hedgehog, DICER, and the Problem With Naming Genes". Pacific Standard. https://psmag.com/environment/sonic-hedgehog-dicer-problem-naming-genes-91386.
- ↑ "Gene of the month - Mothers Against Decapentaplegic". The Naked Scientists. September 9, 2012. https://www.thenakedscientists.com/articles/interviews/gene-month-mothers-against-decapentaplegic.
- ↑ "OMIM Entry - * 600993 - MOTHERS AGAINST DECAPENTAPLEGIC, DROSOPHILA, HOMOLOG OF, 4; SMAD4". Johns Hopkins University. January 18, 1996. https://www.omim.org/entry/600993.
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