Biology:Ngari virus

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Short description: RNA virus

Ngari virus
Virus classification e
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Negarnaviricota
Class: Ellioviricetes
Order: Bunyavirales
Family: Peribunyaviridae
Genus: Orthobunyavirus
Ngari virus

Ngari virus (NRIV)[1] is a single-stranded, negative sense, tri-segmented RNA virus. It is a subtype of the Bunyamwera virus (BUNV) and closely related to the Batai virus (BATV). NRIV is the only reassortment virus of the subtypes. There is evidence suggesting that NRIV stems from a naturally occurring reassortment event in which a host was infected with both BUNV and BATV.[1] It is commonly found in areas that experience an outbreak of Rift Valley fever virus (RFVF)[2]


The primary form of transmission of the virus to humans is through mosquitos.[3] Although mosquitos are the primary source, the virus was also detected in Ixodid ticks found on cattle in Guinea but there is no evidence indicating that they are able to spread the virus.[4] Furthermore, the virus has previously been found within goats and sheep in Mauritania.[5]


The virus has been reported primarily in African countries which include Mauritania, Senegal, Sudan, Central African Republic, DRC, Kenya, Somalia, South Africa, and Madagascar.[3]

Effects in Humans

Humans that are infected by the virus typically develop severe or fatal hemorrhagic fever.[1]


Ngari virus was first isolated in Senegal in 1979 from Aedes simpsoni mosquitos.[3]


  1. 1.0 1.1 1.2 Gerrard, Sonja R.; Li, Li; Barrett, Alan D.; Nichol, Stuart T. (August 2004). "Ngari virus is a Bunyamwera virus reassortant that can be associated with large outbreaks of hemorrhagic fever in Africa". Journal of Virology 78 (16): 8922–8926. doi:10.1128/JVI.78.16.8922-8926.2004. ISSN 0022-538X. PMID 15280501. 
  2. Cichon, Nicole; Barry, Yahya; Stoek, Franziska; Diambar, Abdellah; Ba, Aliou; Ziegler, Ute; Rissmann, Melanie; Schulz, Jana et al. (2021). "Co-circulation of Orthobunyaviruses and Rift Valley Fever Virus in Mauritania, 2015". Frontiers in Microbiology 12: 3524. doi:10.3389/fmicb.2021.766977. ISSN 1664-302X. PMID 35003005. 
  3. 3.0 3.1 3.2 Dutuze, M. Fausta; Nzayirambaho, Manassé; Mores, Christopher N.; Christofferson, Rebecca C. (2018). "A Review of Bunyamwera, Batai, and Ngari Viruses: Understudied Orthobunyaviruses With Potential One Health Implications". Frontiers in Veterinary Science 5: 69. doi:10.3389/fvets.2018.00069. ISSN 2297-1769. PMID 29707545. 
  4. Makenov, M. T.; Toure, A. H.; Bayandin, R. B.; Gladysheva, A. V.; Shipovalov, A. V.; Boumbaly, S.; Sacko, N.; Korneev, M. G. et al. (2020-11-13) (in en). Ngari virus (Orthobunyavirus, Peribunyaviridae) in ixodid ticks collected from cattle in Guinea. pp. 2020.11.10.20228924. doi:10.1101/2020.11.10.20228924. 
  5. Eiden, Martin; Vina-Rodriguez, Ariel; Mamy, Bezeid O. El; Isselmou, Katia; Ziegler, Ute; Höper, Dirk; Jäckel, Susanne; Balkema-Buschmann, Anne et al. (2014). "Ngari Virus in Goats during Rift Valley Fever Outbreak, Mauritania, 2010 - Volume 20, Number 12—December 2014 - Emerging Infectious Diseases journal - CDC" (in en-us). Emerging Infectious Diseases 20 (12): 2174–2176. doi:10.3201/eid2012.140787. PMID 25419696. PMC 4257808. 

Wikidata ☰ Q22940952 entry