Biology:Nodavirus endopeptidase

From HandWiki
Nodavirus endopeptidase
Identifiers
EC number3.4.23.44
CAS number852954-38-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Nodavirus endopeptidase (EC 3.4.23.44, Black Beetle virus endopeptidase, Flock House virus endopeptidase) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Hydrolysis of an asparaginyl bond involved in the maturation of the structural protein of the virus, typically -Asn-Ala- or -Asn-Phe-

The enzyme is coded by several nodaviruses that are insect pathogens.

References

  1. "Capsid assembly in a family of animal viruses primes an autoproteolytic maturation that depends on a single aspartic acid residue". The Journal of Biological Chemistry 269 (18): 13680–4. May 1994. PMID 8175803. 
  2. "Nodavirus endopeptidase". Handbook of Proteolytic Enzymes. London: Handbook of Proteolytic Enzymes. 1998. pp. 964–967. 

External links