Biology:Olivetolic acid cyclase

From HandWiki
Short description: Enzyme
Olivetolic acid cyclase
Identifiers
EC number4.4.1.26
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Olivetolic acid cyclase (EC 4.4.1.26, OAC) is an enzyme with systematic name 3,5,7-trioxododecanoyl-CoA CoA-lyase (2,4-dihydroxy-6-pentylbenzoate-forming).[1] This enzyme catalyses the following chemical reaction

3,5,7-trioxododecanoyl-CoA → CoA + 2,4-dihydroxy-6-pentylbenzoate

This enzymes participates in the cannabinoids biosynthesis in the plant Cannabis sativa.

References

  1. "Identification of olivetolic acid cyclase from Cannabis sativa reveals a unique catalytic route to plant polyketides". Proceedings of the National Academy of Sciences of the United States of America 109 (31): 12811–6. July 2012. doi:10.1073/pnas.1200330109. PMID 22802619. Bibcode2012PNAS..10912811G. 

External links