Biology:Opacity porins

From HandWiki
Opacity family porin protein
PDB 1p4t EBI.jpg
Structure of Neisserial surface protein A (NspA).[1]
Identifiers
SymbolOpacity
PfamPF02462
InterProIPR003394
SCOP21p4t / SCOPe / SUPFAM
OPM superfamily235
OPM protein1p4t

Opacity family porins are a family of porins from pathogenic Neisseria. These bacteria possess a repertoire of phase-variable opacity proteins that mediate various pathogen/host cell interactions.[2] These proteins are related to OmpA-like transmembrane domain family.

References

  1. "Crystal structure of Neisserial surface protein A (NspA), a conserved outer membrane protein with vaccine potential". J. Biol. Chem. 278 (27): 24825–30. July 2003. doi:10.1074/jbc.M302803200. PMID 12716881. 
  2. "The role of neisserial Opa proteins in interactions with host cells". Trends Microbiol. 6 (12): 489–495. 1998. doi:10.1016/S0966-842X(98)01365-1. PMID 10036728.