Biology:Oxepin-CoA hydrolase

From HandWiki
Oxepin-CoA hydrolase
Identifiers
EC number3.7.1.16
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Oxepin-CoA hydrolase (EC 3.7.1.16, paaZ (gene)) is an enzyme with systematic name 2-oxepin-2(3H)-ylideneacetyl-CoA hydrolyase.[1][2][3][4] This enzyme catalyses the following chemical reaction

2-oxepin-2(3H)-ylideneacetyl-CoA + H2O [math]\displaystyle{ \rightleftharpoons }[/math] 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde

The enzyme is present in bacteria Escherichia coli.

References

  1. "Catabolism of phenylacetic acid in Escherichia coli. Characterization of a new aerobic hybrid pathway". The Journal of Biological Chemistry 273 (40): 25974–86. October 1998. doi:10.1074/jbc.273.40.25974. PMID 9748275. 
  2. "Identification and characterization of a new enoyl coenzyme A hydratase involved in biosynthesis of medium-chain-length polyhydroxyalkanoates in recombinant Escherichia coli". Journal of Bacteriology 185 (18): 5391–7. September 2003. doi:10.1128/jb.185.18.5391-5397.2003. PMID 12949091. PMC 193764. http://koasas.kaist.ac.kr/bitstream/10203/21887/1/int119.pdf. 
  3. "Functional genomics by NMR spectroscopy. Phenylacetate catabolism in Escherichia coli". European Journal of Biochemistry 270 (14): 3047–54. July 2003. doi:10.1046/j.1432-1033.2003.03683.x. PMID 12846838. 
  4. "Bacterial phenylalanine and phenylacetate catabolic pathway revealed". Proceedings of the National Academy of Sciences of the United States of America 107 (32): 14390–5. August 2010. doi:10.1073/pnas.1005399107. PMID 20660314. 

External links