Biology:P97
From HandWiki
Short description: Class of enzymes
p97 also known as VCP (Cdc48 in yeast) is a hexameric ATPase of the AAA family which disassembles SNARE proteins after membrane fusion.[1] It is involved in a fusion of homotypic membranes, protein degradation, and activation of membrane-bound transcription factors.[2]
References
- ↑ Zhang, X; Shaw, A; Bates, PA; Newman, RH; Gowen, B; Orlova, E; Gorman, MA; Kondo, H et al. (2000). "Structure of the AAA ATPase p97". Molecular Cell 6 (6): 1473–84. doi:10.1016/s1097-2765(00)00143-x. PMID 11163219.
- ↑ Madsen, L.; Seeger, M.; Semple, CA.; Hartmann-Petersen, R. (Dec 2009). "New ATPase regulators--p97 goes to the PUB.". Int J Biochem Cell Biol 41 (12): 2380–8. doi:10.1016/j.biocel.2009.05.017. PMID 19497384.
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