Biology:PASD1
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
PAS domain-containing protein 1 is a protein that in humans is encoded by the PASD1 gene.[1][2][3]
PASD1 has been shown to inhibit the transcriptional activity between CLOCK and BMAL1 which appears to be co-opted in cancer cells to attenuate clock function.[4][5]
References
- ↑ "Serologic detection of diffuse large B-cell lymphoma-associated antigens". International Journal of Cancer 110 (4): 563–569. July 2004. doi:10.1002/ijc.20170. PMID 15122589.
- ↑ "A novel diffuse large B-cell lymphoma-associated cancer testis antigen encoding a PAS domain protein". British Journal of Cancer 91 (1): 141–149. July 2004. doi:10.1038/sj.bjc.6601875. PMID 15162151.
- ↑ "Entrez Gene: PASD1 PAS domain containing 1". https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=139135.
- ↑ "Cancer/Testis Antigen PASD1 Silences the Circadian Clock". Molecular Cell 58 (5): 743–754. June 2015. doi:10.1016/j.molcel.2015.03.031. PMID 25936801.
- ↑ "How the Body's Trillions of Clocks Keep Time". 15 September 2015. https://www.quantamagazine.org/how-the-bodys-trillions-of-clocks-keep-time-20150915/.
Further reading
- "DNA cloning using in vitro site-specific recombination". Genome Research 10 (11): 1788–1795. November 2000. doi:10.1101/gr.143000. PMID 11076863.
- "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports 1 (3): 287–292. September 2000. doi:10.1093/embo-reports/kvd058. PMID 11256614.
- "Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia". Biochemical and Biophysical Research Communications 335 (4): 1293–1304. October 2005. doi:10.1016/j.bbrc.2005.08.024. PMID 16112646. Bibcode: 2005BBRC..335.1293G.
- "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research 16 (1): 55–65. January 2006. doi:10.1101/gr.4039406. PMID 16344560.
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