Biology:PCNA-associated factor
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
PCNA-associated factor (also called “PCNA clamp associated factor”) is a protein that in humans is encoded by the PCLAF gene (previously KIAA0101).[1][2][3] The PCLAF protein binds to PCNA and regulates DNA repair during DNA replication.[4]
Interactions
PCLAF has been shown to interact with PCNA.[1]
References
- ↑ 1.0 1.1 "p15(PAF), a novel PCNA associated factor with increased expression in tumor tissues". Oncogene 20 (4): 484–9. Jan 2001. doi:10.1038/sj.onc.1204113. PMID 11313979.
- ↑ "The PCNA-associated factor KIAA0101/p15(PAF) binds the potential tumor suppressor product p33ING1b". Experimental Cell Research 312 (1): 73–85. Jan 2006. doi:10.1016/j.yexcr.2005.09.020. PMID 16288740.
- ↑ "Entrez Gene: KIAA0101 KIAA0101". https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=9768.
- ↑ "Q15004 · PAF15_HUMAN". UniProt consortium. https://www.uniprot.org/uniprotkb/Q15004/entry.
Further reading
- "NS5ATP9, a gene up-regulated by HCV NS5A protein". Cancer Letters 259 (2): 192–7. Feb 2008. doi:10.1016/j.canlet.2007.10.029. PMID 18068894.
- "KIAA0101 (OEACT-1), an expressionally down-regulated and growth-inhibitory gene in human hepatocellular carcinoma". BMC Cancer 6. 2006. doi:10.1186/1471-2407-6-109. PMID 16646990.
- "Overexpressed in anaplastic thyroid carcinoma-1 (OEATC-1) as a novel gene responsible for anaplastic thyroid carcinoma". Cancer 103 (9): 1785–90. May 2005. doi:10.1002/cncr.20988. PMID 15789362.
- "Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer". Oncogene 23 (46): 7734–45. Oct 2004. doi:10.1038/sj.onc.1207921. PMID 15334068.
- "Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1". DNA Research 2 (1): 37–43. 1995. doi:10.1093/dnares/2.1.37. PMID 7788527.
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