Biology:Prehormone
From HandWiki
Short description: Class of chemical compounds
A prehormone is a biochemical substance secreted by glandular tissue and has minimal or no significant biological activity, but it is converted in peripheral tissues into an active hormone. Calcifediol is an example of a prehormone which is produced by hydroxylation of vitamin D3 (cholecalciferol) in the liver.[1] Another example is adrenal androgens like dehydroepiandrosterone and androstenedione, which can be converted into testosterone and dihydrotestosterone.[2]
See also
References
- ↑ Dabek, Jan T. (1997-01-01), Bittar, E. Edward; Bittar, Neville, eds., "Chapter 47 The prehormone vitamin D" (in en), Principles of Medical Biology, Molecular and Cellular Pharmacology (Elsevier) 8: pp. 933–949, doi:10.1016/s1569-2582(97)80108-0, ISBN 9781559388139, https://www.sciencedirect.com/science/article/pii/S1569258297801080, retrieved 2022-09-16
- ↑ "DHEA, Important Source of Sex Steroids in Men and Even More in Women". Neuroendocrinology - Pathological Situations and Diseases. Progress in Brain Research. 182. 2010. 97–148. doi:10.1016/S0079-6123(10)82004-7. ISBN 9780444536167.
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