Biology:Preprotachykinin
From HandWiki
Preprotachykinins are precursor proteins that are modified into tachykinin peptides. Via alternative splicing and post-translational modifications, preprotachykinins produce multiple peptide neurotransmitters. There are two human preprotachykinins:[1]
- preprotachykinin-1 (also PPT-1, PPT-I, or PPT-A), which produces substance P and neurokinin A (also called "substance K"), and the derived neuropeptide K and neurokinin gamma.
- preprotachykinin-2 (also PPT-2, PPT-II, or PPT-B), which produces neurokinin B.
References
- ↑ "Diversity in mammalian tachykinin peptidergic neurons: multiple peptides, receptors, and regulatory mechanisms". FASEB Journal 4 (6): 1606–15. 1 April 1990. doi:10.1096/fasebj.4.6.1969374. PMID 1969374.
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