Biology:Projectome

From HandWiki

A projectome is a database or list of all neural connections made by neurons that project from one structure of the nervous system (e.g. a ganglion or a brain nucleus) to another. Thus, a projectome is a subset of a connectome, since a connectome lists not only the connections between the structures, but also within them. Once a complete connectome of an organism is known, the projectome can be derived from it.[1][2][3]

Projectomics, a branch of neuroinformatics, is defined as long-range connectomics.[4] Term projectome was introduced in 2007 by Kasthuri and Lichtman.[5]

References

  1. Chu, Abby (2024-01-05). "Mapping the Projectome Using Compresstome Vibratome" (in en-US). https://precisionary.com/mapping-the-projectome-using-compresstome-vibratome/. 
  2. Wildenberg, Gregg et al. (2023-10-24) (in en), A Pipeline for a Primate Projectome: mapping every individual myelinated axon across the whole brain, bioRxiv, doi:10.1101/2023.10.23.563679, https://www.biorxiv.org/content/10.1101/2023.10.23.563679v1, retrieved 2025-09-29 
  3. "Mapping the Brain: The Largest Neuron Projectome Unveiled" (in en-US). 2024-02-01. https://neurosciencenews.com/hippocampus-projectome-25550/. 
  4. Nguyen, Tri et al. (2023), The XPRESS Challenge: Xray Projectomic Reconstruction -- Extracting Segmentation with Skeletons 
  5. Kasthuri, Narayanan; Lichtman, Jeff W (2007-04-01). "The rise of the 'projectome'" (in en). Nature Methods 4 (4): 307–308. doi:10.1038/nmeth0407-307. ISSN 1548-7091. PMID 17396125. https://www.nature.com/articles/nmeth0407-307.