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Short description: Drug given during chemotherapy to increase blood cell regeneration

Promegapoietin is a drug given during chemotherapy to increase blood cell regeneration. It is a colony-stimulating factor that stimulates megakaryocyte production.[1][2]

It functions by stimulating ligands for interleukin 3 and c-Mpl.[3]


  1. "Effective ex vivo generation of megakaryocytic cells from mobilized peripheral blood CD34(+) cells with stem cell factor and promegapoietin". Exp Hematol 28 (3): 335–46. 2000. doi:10.1016/S0301-472X(99)00152-6. PMID 10720698. 
  2. Definition of promegapoietin – NCI Dictionary of Cancer Terms
  3. "Promegapoietin, a family of chimeric growth factors, supports megakaryocyte development through activation of IL-3 and c-Mpl ligand signaling pathways". Exp Hematol 29 (10): 1177–84. 2001. doi:10.1016/S0301-472X(01)00694-4. PMID 11602319. 

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