Biology:Protein BTG3
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Protein BTG3 is a protein that in humans is encoded by the BTG3 gene.[1][2]
The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein might play a role in neurogenesis in the central nervous system.[2]
References
- ↑ "ANA, a novel member of Tob/BTG1 family, is expressed in the ventricular zone of the developing central nervous system". Oncogene 16 (20): 2687–93. Jun 1998. doi:10.1038/sj.onc.1201805. PMID 9632145.
- ↑ 2.0 2.1 "Entrez Gene: BTG3 BTG family, member 3". https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=10950.
External links
- Human BTG3 genome location and BTG3 gene details page in the UCSC Genome Browser.
Further reading
- "In search of a function for the TIS21/PC3/BTG1/TOB family". FEBS Lett. 497 (2–3): 67–72. 2001. doi:10.1016/S0014-5793(01)02436-X. PMID 11377414. Bibcode: 2001FEBSL.497...67M.
- Guéhenneux F; Duret L; Callanan MB; Bouhas, R; Hayette, S; Berthet, C; Samarut, C; Rimokh, R et al. (1997). "Cloning of the mouse BTG3 gene and definition of a new gene family (the BTG family) involved in the negative control of the cell cycle". Leukemia 11 (3): 370–5. doi:10.1038/sj.leu.2400599. PMID 9067576.
- Hattori M; Fujiyama A; Taylor TD; Taylor, T. D.; Watanabe, H.; Yada, T.; Park, H.-S.; Toyoda, A. et al. (2000). "The DNA sequence of human chromosome 21". Nature 405 (6784): 311–9. doi:10.1038/35012518. PMID 10830953. Bibcode: 2000Natur.405..311H.
- Birot A; Duret L; Bartholin L; Santalucia, Bénédicte; Tigaud, Isabelle; Magaud, Jean-Pierre; Rouault, Jean-Pierre (2000). "Identification and molecular analysis of BANP". Gene 253 (2): 189–96. doi:10.1016/S0378-1119(00)00244-4. PMID 10940556.
- "Association of ANA, a member of the antiproliferative Tob family proteins, with a Caf1 component of the CCR4 transcriptional regulatory complex". Jpn. J. Cancer Res. 92 (6): 592–6. 2001. doi:10.1111/j.1349-7006.2001.tb01135.x. PMID 11429045.
- Strausberg RL; Feingold EA; Grouse LH; Derge, JG; Klausner, RD; Collins, FS; Wagner, L; Shenmen, CM et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- Gerhard DS; Wagner L; Feingold EA; Shenmen, CM; Grouse, LH; Schuler, G; Klein, SL; Old, S et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Rual JF; Venkatesan K; Hao T; Hirozane-Kishikawa, Tomoko; Dricot, Amélie; Li, Ning; Berriz, Gabriel F.; Gibbons, Francis D. et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
- Lim J; Hao T; Shaw C; Patel, Akash J.; Szabó, Gábor; Rual, Jean-François; Fisk, C. Joseph; Li, Ning et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
- Ou YH; Chung PH; Hsu FF; Sun, Te-Ping; Chang, Wen-Ying; Shieh, Sheau-Yann (2007). "The candidate tumor suppressor BTG3 is a transcriptional target of p53 that inhibits E2F1". EMBO J. 26 (17): 3968–80. doi:10.1038/sj.emboj.7601825. PMID 17690688.
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