Biology:Protein therapeutics
From HandWiki
Protein therapeutics are proteins used as experimental or approved therapies for disease states. They include "monoclonal antibodies (mAbs), peptide hormones, growth factors, plasma proteins, enzymes, and hemolytic factors"[1] While proteins can be more specific and flexible in their mechanism of action compared to small-molecule drugs, duration of action and drug delivery can be a challenge.[2][3][4]
References
- ↑ Ramesh, Rajendran; Ravichandran, Ramakrishnan (2023). "Approved Protein Therapeutics and Their Biochemical Targets" (in en). Protein-based Therapeutics. Springer Nature. p. 199. ISBN 978-981-19-8249-1. https://link.springer.com/chapter/10.1007/978-981-19-8249-1_7.
- ↑ Varanko, Anastasia; Saha, Soumen; Chilkoti, Ashutosh (2020). "Recent trends in protein and peptide-based biomaterials for advanced drug delivery". Advanced Drug Delivery Reviews 156: 133–187. doi:10.1016/j.addr.2020.08.008.
- ↑ Zaman, Rahela; Islam, Rowshan Ara; Ibnat, Nabilah; Othman, Iekhsan; Zaini, Anuar; Lee, Chooi Yeng; Chowdhury, Ezharul Hoque (May 2019). "Current strategies in extending half-lives of therapeutic proteins". Journal of Controlled Release 301: 176–189. doi:10.1016/j.jconrel.2019.02.016.
- ↑ Qin, Xiaofei; Yu, Changmin; Wei, Jing; Li, Lin; Zhang, Chengwu; Wu, Qiong; Liu, Jinhua; Yao, Shao Q. et al. (November 2019). "Rational Design of Nanocarriers for Intracellular Protein Delivery". Advanced Materials 31 (46). doi:10.1002/adma.201902791.
Further reading
- Sauna, Zuben E.; Kimchi-Sarfaty, Chava (2017) (in en). Protein Therapeutics. Springer. ISBN 978-3-319-41818-6. https://books.google.com/books/about/Protein_Therapeutics.html?id=UNYtDwAAQBAJ&source=kp_book_description.
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