Biology:Pyridoxamine—oxaloacetate transaminase

From HandWiki
pyridoxamine-oxaloacetate transaminase
Identifiers
EC number2.6.1.31
CAS number37277-88-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a pyridoxamine-oxaloacetate transaminase (EC 2.6.1.31) is an enzyme that catalyzes the chemical reaction:

pyridoxamine + oxaloacetate [math]\displaystyle{ \rightleftharpoons }[/math] pyridoxal + L-aspartate

Thus, the two substrates of this enzyme are pyridoxamine and oxaloacetate, whereas its two products are pyridoxal and L-aspartate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is pyridoxamine:oxaloacetate aminotransferase. This enzyme participates in vitamin B6 metabolism.

References

Further reading

  • "Enzymatic transamination of pyridoxamine. I. With oxaloacetate and alpha-ketoglutarate". The Journal of Biological Chemistry 237: 127–32. January 1962. PMID 14004226. 
  • "PYRIDOXAMINE-OXALOACETIC TRANSAMINASE OF RAT KIDNEY". The Journal of Biological Chemistry 239: 1492–7. May 1964. PMID 14189882.