Biology:RAB1A
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Short description: Protein-coding gene in the species Homo sapiens
![]() Generic protein structure example |
Ras-related protein Rab-1A is a protein that in humans is encoded by the RAB1A gene.[1][2]
Interactions
RAB1A has been shown to interact with:
References
- ↑ "The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion". The Journal of Biological Chemistry 264 (21): 12394–401. Jul 1989. doi:10.1016/S0021-9258(18)63872-4. PMID 2501306.
- ↑ "Entrez Gene: RAB1A RAB1A, member RAS oncogene family". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5861.
- ↑ 3.0 3.1 "REP-2, a Rab escort protein encoded by the choroideremia-like gene". The Journal of Biological Chemistry 269 (3): 2111–7. Jan 1994. doi:10.1016/S0021-9258(17)42142-9. PMID 8294464.
- ↑ "Mechanism of Rab geranylgeranylation: formation of the catalytic ternary complex". Biochemistry 37 (36): 12559–68. Sep 1998. doi:10.1021/bi980881a. PMID 9730828.
- ↑ 5.0 5.1 "MICAL-1 isoforms, novel rab1 interacting proteins". Biochemical and Biophysical Research Communications 306 (1): 79–86. Jun 2003. doi:10.1016/s0006-291x(03)00918-5. PMID 12788069.
- ↑ "Identification of rabaptin-5, rabex-5, and GM130 as putative effectors of rab33b, a regulator of retrograde traffic between the Golgi apparatus and ER". FEBS Letters 508 (2): 201–9. Nov 2001. doi:10.1016/s0014-5793(01)02993-3. PMID 11718716.
- ↑ "A GRASP55-rab2 effector complex linking Golgi structure to membrane traffic". The Journal of Cell Biology 155 (6): 877–83. Dec 2001. doi:10.1083/jcb.200108079. PMID 11739401.
- ↑ "Golgin-84 is a rab1 binding partner involved in Golgi structure". Traffic 4 (3): 153–61. Mar 2003. doi:10.1034/j.1600-0854.2003.00103.x. PMID 12656988.
- ↑ "The coiled-coil membrane protein golgin-84 is a novel rab effector required for Golgi ribbon formation". The Journal of Cell Biology 160 (2): 201–12. Jan 2003. doi:10.1083/jcb.200207045. PMID 12538640.
- ↑ "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. Oct 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
- ↑ "Isolation and characterization of a dual prenylated Rab and VAMP2 receptor". The Journal of Biological Chemistry 272 (43): 26991–8. Oct 1997. doi:10.1074/jbc.272.43.26991. PMID 9341137.
Further reading
- "Phosphorylation of two small GTP-binding proteins of the Rab family by p34cdc2". Nature 350 (6320): 715–8. Apr 1991. doi:10.1038/350715a0. PMID 1902553. Bibcode: 1991Natur.350..715B.
- "Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A". Proceedings of the National Academy of Sciences of the United States of America 91 (25): 11963–7. Dec 1994. doi:10.1073/pnas.91.25.11963. PMID 7991565. Bibcode: 1994PNAS...9111963F.
- "REP-2, a Rab escort protein encoded by the choroideremia-like gene". The Journal of Biological Chemistry 269 (3): 2111–7. Jan 1994. doi:10.1016/S0021-9258(17)42142-9. PMID 8294464.
- "Identification of small GTP-binding rab proteins in human platelets: thrombin-induced phosphorylation of rab3B, rab6, and rab8 proteins". Proceedings of the National Academy of Sciences of the United States of America 90 (16): 7647–51. Aug 1993. doi:10.1073/pnas.90.16.7647. PMID 8356066. Bibcode: 1993PNAS...90.7647K.
- "YAC contigs of the Rab1 and wobbler (wr) spinal muscular atrophy gene region on proximal mouse chromosome 11 and of the homologous region on human chromosome 2p". Genomics 32 (3): 447–54. Mar 1996. doi:10.1006/geno.1996.0140. PMID 8838809. https://www.pure.ed.ac.uk/ws/files/12562598/Wedemeyer_Genomics_1996.pdf.
- "Isolation and characterization of a dual prenylated Rab and VAMP2 receptor". The Journal of Biological Chemistry 272 (43): 26991–8. Oct 1997. doi:10.1074/jbc.272.43.26991. PMID 9341137.
- "Mechanism of Rab geranylgeranylation: formation of the catalytic ternary complex". Biochemistry 37 (36): 12559–68. Sep 1998. doi:10.1021/bi980881a. PMID 9730828.
- "Cloning of Rab GTPases expressed in human skeletal muscle: studies in insulin-resistant subjects". Hormone and Metabolic Research 30 (11): 656–62. Nov 1998. doi:10.1055/s-2007-978953. PMID 9918381.
- "Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion". Science 289 (5478): 444–8. Jul 2000. doi:10.1126/science.289.5478.444. PMID 10903204. Bibcode: 2000Sci...289..444A.
- "DNA cloning using in vitro site-specific recombination". Genome Research 10 (11): 1788–95. Nov 2000. doi:10.1101/gr.143000. PMID 11076863.
- "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research 11 (3): 422–35. Mar 2001. doi:10.1101/gr.GR1547R. PMID 11230166.
- "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports 1 (3): 287–92. Sep 2000. doi:10.1093/embo-reports/kvd058. PMID 11256614.
- "Rab1 interaction with a GM130 effector complex regulates COPII vesicle cis--Golgi tethering". Traffic 2 (4): 268–76. Apr 2001. doi:10.1034/j.1600-0854.2001.1o007.x. PMID 11285137.
- "Road Rage: Cardiac Rab1 and ER-to-Golgi Traffic". Circulation Research 89 (12): 1087–8. Dec 2001. doi:10.1161/res.89.12.1087. PMID 11739271.
- "A GRASP55-rab2 effector complex linking Golgi structure to membrane traffic". The Journal of Cell Biology 155 (6): 877–83. Dec 2001. doi:10.1083/jcb.200108079. PMID 11739401.
- "The coiled-coil membrane protein golgin-84 is a novel rab effector required for Golgi ribbon formation". The Journal of Cell Biology 160 (2): 201–12. Jan 2003. doi:10.1083/jcb.200207045. PMID 12538640.
- "Golgin-84 is a rab1 binding partner involved in Golgi structure". Traffic 4 (3): 153–61. Mar 2003. doi:10.1034/j.1600-0854.2003.00103.x. PMID 12656988.
- "MICAL-1 isoforms, novel rab1 interacting proteins". Biochemical and Biophysical Research Communications 306 (1): 79–86. Jun 2003. doi:10.1016/S0006-291X(03)00918-5. PMID 12788069.