Biology:RALBP1

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

RalA-binding protein 1 is a protein that in humans is encoded by the RALBP1 gene.

Interactions

RALBP1 has been shown to interact with:

• Cyclin B1,
• HSF1,
• RALA,
• RALB, and
• REPS2.

Further reading

• "RLIP76, a novel transporter catalyzing ATP-dependent efflux of xenobiotics". Drug Metab. Dispos. 30 (12): 1300–10. 2003. doi:10.1124/dmd.30.12.1300. PMID 12433796. 
• "An Eps homology (EH) domain protein that binds to the Ral-GTPase target, RalBP1". J. Biol. Chem. 272 (50): 31230–4. 1998. doi:10.1074/jbc.272.50.31230. PMID 9395447. 
• "Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral". J. Biol. Chem. 273 (2): 814–21. 1998. doi:10.1074/jbc.273.2.814. PMID 9422736. 
• "Identification and characterization in Xenopus of XsmgGDS, a RalB binding protein". Biochem. Biophys. Res. Commun. 250 (2): 359–63. 1998. doi:10.1006/bbrc.1998.9336. PMID 9753634. 
• "Involvement of Ras and Ral in Chemotactic Migration of Skeletal Myoblasts". Mol. Cell. Biol. 20 (13): 4658–65. 2000. doi:10.1128/MCB.20.13.4658-4665.2000. PMID 10848592. 
• "RLIP76, an effector of the GTPase Ral, interacts with the AP2 complex: involvement of the Ral pathway in receptor endocytosis". J. Cell Sci. 113 (16): 2837–44. 2000. doi:10.1242/jcs.113.16.2837. PMID 10910768. https://hal.inrae.fr/hal-02696179/file/2000-Jullien-Flores_J%20cell%20Sci_1.pdf. 
• "Novel function of human RLIP76: ATP-dependent transport of glutathione conjugates and doxorubicin". Biochemistry 39 (31): 9327–34. 2000. doi:10.1021/bi992964c. PMID 10924126. 
• "RLIP76 is the major ATP-dependent transporter of glutathione-conjugates and doxorubicin in human erythrocytes". Arch. Biochem. Biophys. 391 (2): 171–9. 2001. doi:10.1006/abbi.2001.2395. PMID 11437348. 
• "Purification and functional reconstitution of intact ral-binding Gtpase activating protein, RLIP76, in artificial liposomes". Acta Biochim. Pol. 48 (2): 551–62. 2002. doi:10.18388/abp.2001_3938. PMID 11732624. 
• "Regulation of endocytosis of activin type II receptors by a novel PDZ protein through Ral/Ral-binding protein 1-dependent pathway". J. Biol. Chem. 277 (21): 19008–18. 2002. doi:10.1074/jbc.M112472200. PMID 11882656. 
• "Role of RLIP76 in lung cancer doxorubicin resistance: I. The ATPase activity of RLIP76 correlates with doxorubicin and 4-hydroxynonenal resistance in lung cancer cells". Int. J. Oncol. 22 (2): 365–75. 2003. doi:10.3892/ijo.22.2.365. PMID 12527936. 
• "Role of RLIP76 in lung cancer doxorubicin resistance: II. Doxorubicin transport in lung cancer by RLIP76". Int. J. Oncol. 22 (4): 713–20. 2003. doi:10.3892/ijo.22.4.713. PMID 12632060. 
• "Role of RLIP76 in lung cancer doxorubicin resistance: III. Anti-RLIP76 antibodies trigger apoptosis in lung cancer cells and synergistically increase doxorubicin cytotoxicity". Int. J. Oncol. 22 (4): 721–32. 2003. doi:10.3892/ijo.22.4.721. PMID 12632061. 
• "RLIP, an effector of the Ral GTPases, is a platform for Cdk1 to phosphorylate epsin during the switch off of endocytosis in mitosis". J. Biol. Chem. 278 (33): 30597–604. 2003. doi:10.1074/jbc.M302191200. PMID 12775724. 
• "Ral GTPases regulate exocyst assembly through dual subunit interactions". J. Biol. Chem. 278 (51): 51743–8. 2004. doi:10.1074/jbc.M308702200. PMID 14525976. 
• "Staphylococcus aureus protein A induces airway epithelial inflammatory responses by activating TNFR1". Nat. Med. 10 (8): 842–8. 2004. doi:10.1038/nm1079. PMID 15247912. 
• "AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation". J. Biol. Chem. 279 (43): 44955–65. 2004. doi:10.1074/jbc.M407617200. PMID 15310755.