Biology:RCBTB2
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
RCC1 and BTB domain-containing protein 2 is a protein that in humans is encoded by the RCBTB2 gene.[1][2]
This gene encodes a member of the RCC1-related GEF family. The N-terminal half of the encoded amino acid sequence shows similarity to the regulator of chromosome condensation RCC1, which acts as a guanine nucleotide exchange factor (GEF) protein for the Ras-related GTPase Ran.[2]
References
- ↑ "cDNA cloning, gene characterization and 13q14.3 chromosomal assignment of CHC1-L, a chromosome condensation regulator-like guanine nucleotide exchange factor". Genomics 54 (1): 99–106. Jan 1999. doi:10.1006/geno.1998.5498. PMID 9806834.
- ↑ 2.0 2.1 "Entrez Gene: RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1102.
Further reading
- Rual JF; Venkatesan K; Hao T et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
- Gerhard DS; Wagner L; Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Dunham A; Matthews LH; Burton J et al. (2004). "The DNA sequence and analysis of human chromosome 13". Nature 428 (6982): 522–8. doi:10.1038/nature02379. PMID 15057823. Bibcode: 2004Natur.428..522D.
- Ota T; Suzuki Y; Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Strausberg RL; Feingold EA; Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- Latil A; Morant P; Fournier G et al. (2002). "CHC1-L, a candidate gene for prostate carcinogenesis at 13q14.2, is frequently affected by loss of heterozygosity and underexpressed in human prostate cancer". Int. J. Cancer 99 (5): 689–96. doi:10.1002/ijc.10393. PMID 12115502.
- Renault L; Nassar N; Wittinghofer A et al. (1999). "Crystallization and preliminary X-ray analysis of human RCC1, the regulator of chromosome condensation". Acta Crystallogr. D 55 (Pt 1): 272–5. doi:10.1107/S0907444998007768. PMID 10089422.
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