Biology:RMST (gene)
From HandWiki
 Generic protein structure example |
Rhabdomyosarcoma 2 associated transcript (RMST) is a long non-coding RNA. In humans, it is located on chromosome 12q21. It is expressed at higher levels in alveolar rhabdomyosarcoma than in embryonal rhabdomyosarcoma.[1] In the brain, RMST is expressed in the developing ventral midbrain where dopaminergic neurons are formed, the developing isthmus and in the dorsal midline cells of the rostral neural tube.[2] In the midbrain-hindbrain boundary region, its expression is regulated by PAX2.[3]
See also
- Long noncoding RNA
References
- ↑ "Identification of a novel gene NCRMS on chromosome 12q21 with differential expression between rhabdomyosarcoma subtypes". Oncogene 21 (19): 3029–3037. May 2002. doi:10.1038/sj.onc.1205460. PMID 12082533.
- ↑ "Rmst is a novel marker for the mouse ventral mesencephalic floor plate and the anterior dorsal midline cells". PLOS ONE 5 (1): e8641. 2010. doi:10.1371/journal.pone.0008641. PMID 20062813. Bibcode: 2010PLoSO...5.8641U.
- ↑ "Identification of Pax2-regulated genes by expression profiling of the mid-hindbrain organizer region". Development 132 (11): 2633–2643. June 2005. doi:10.1242/dev.01833. PMID 15872005.
Further reading
- "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–45. 2004. doi:10.1038/ng1285. PMID 14702039.
 |  |
