Biology:RNF167
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Ring finger protein 167 is a protein that in humans is encoded by the RNF167 gene.[1]
Function
RNF167 is an E3 ubiquitin ligase that interacts with TSSC5 (SLC22A18; MIM 602631) and, together with UBCH6 (UBE2E1; MIM 602916), facilitates TSSC5 polyubiquitylation.[2]
References
- ↑ "Entrez Gene: Ring finger protein 167". https://www.ncbi.nlm.nih.gov/gene/26001.
- ↑ Yamada, H. Y.; Gorbsky, G. J. (March 2006). "Tumor suppressor candidate TSSC5 is regulated by UbcH6 and a novel ubiquitin ligase RING105". Oncogene 25 (9): 1330–1339. doi:10.1038/sj.onc.1209167. ISSN 1476-5594. PMC 2713668. https://www.nature.com/articles/1209167.
Further reading
- "Ubiquitin ligase RNF167 regulates AMPA receptor-mediated synaptic transmission". Proc. Natl. Acad. Sci. U.S.A. 109 (47): 19426–31. November 2012. doi:10.1073/pnas.1217477109. PMID 23129617. Bibcode: 2012PNAS..10919426L.
- "Goliath family E3 ligases regulate the recycling endosome pathway via VAMP3 ubiquitylation". EMBO J. 32 (4): 524–37. February 2013. doi:10.1038/emboj.2013.1. PMID 23353890.
- "Tumour-associated mutations of PA-TM-RING ubiquitin ligases RNF167/RNF13 identify the PA domain as a determinant for endosomal localization". Biochem. J. 459 (1): 27–36. April 2014. doi:10.1042/BJ20131067. PMID 24387786.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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