Biology:Radula marginata

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Short description: Species of liverwort

Radula marginata
Scientific classification edit
Kingdom: Plantae
Division: Marchantiophyta
Class: Jungermanniopsida
Order: Porellales
Family: Radulaceae
Genus: Radula
Species:
R. marginata
Binomial name
Radula marginata
(Hook.f. & Taylor) Gottsche, Lindenb. & Nees

Radula marginata, or Wairuakohu, is a species of plant in the genus Radula,[1] a genus of liverworts. It is endemic to New Zealand.[2][3] It has been found to contain cannabinoids.[4][5]

Cannabinoids

Users smoking the plant have experienced different effects.[6][citation needed] The cannabinoid is not THC, the main psychoactive chemical in cannabis, but it is of similar molecular structure.[4] The liverwort contains perrottetinene and perrottetinenic acid.[4] The quantity of cannabinoid present is much less than in cannabis. Perrottetinene has been shown to be a moderately potent CB1 agonist leading to mild psychoactive effects in mice.[7]

Legal status

The liverwort grows as a common weed.[citation needed] Owning, growing and distributing the liverwort is legal.

Radula marginata may have been used in rongoā (Māori herbal medicine), but there is no firm evidence of this.

References

  1. Hussain, Tajammul; Espley, Richard V.; Gertsch, Jürg; Whare, Tracey; Stehle, Felix; Kayser, Oliver (2019). "Demystifying the liverwort Radula marginata, a critical review on its taxonomy, genetics, cannabinoid phytochemistry and pharmacology". Phytochemistry Reviews 18 (3): 953–965. doi:10.1007/s11101-019-09638-8. 
  2. "GBIF2550163". Discover Life. 2013-05-21. http://www.discoverlife.org/mp/20l?id=GBIF2550163. Retrieved 2022-08-25. 
  3. "GBIF2550057". Discover Life. 2013-05-21. http://www.discoverlife.org/mp/20l?id=GBIF2550057. Retrieved 2022-08-25. 
  4. 4.0 4.1 4.2 Toyota, M. (2002). "New bibenzyl cannabinoid from the New Zealand liverwort Radula marginata". Chem Pharm Bull 50 (10): 1390–1392. doi:10.1248/cpb.50.1390. PMID 12372871. http://cpb.pharm.or.jp/cpb/200210/c10_1390.pdf. 
  5. Hussain, Tajammul; Plunkett, Blue; Ejaz, Mahwish; Espley, Richard V.; Kayser, Oliver (2018). "Identification of Putative Precursor Genes for the Biosynthesis of Cannabinoid-Like Compound in Radula marginata". Frontiers in Plant Science 9: 537. doi:10.3389/fpls.2018.00537. PMID 29868043. 
  6. "Radula Marginata (Perrottetinene) - TripMe Forums - Life | Drugs | Music | Knowledge". http://www.tripme.co.nz/forums/showthread.php?t=1943. 
  7. Chicca, A.; Schafroth, M. A.; Reynoso-Moreno, I.; Erni, R.; Petrucci, V.; Carreira, E. M.; Gertsch, J. (2018-10-01). "Uncovering the psychoactivity of a cannabinoid from liverworts associated with a legal high" (in en). Science Advances 4 (10): eaat2166. doi:10.1126/sciadv.aat2166. ISSN 2375-2548. PMID 30397641. Bibcode2018SciA....4.2166C. 

Wikidata ☰ Q7281740 entry