Biology:Replichore
From HandWiki
The Escherichia coli chromosome shows two main levels of global organization, macrodomains and replichores.[1] In E. coli chromosomes, the origin and terminus of replication divide the genome into oppositely replicated halves called replichores. Replichore 1, which is replicated clockwise, has the presented strand of E. coli as its leading strand; in replichore 2 the complementary strand is the leading one. Many features of E. coli are oriented with respect to replication.[2]
References
- ↑ "Roles for replichores and macrodomains in segregation of the Escherichia coli chromosome". EMBO Rep. 6 (6): 557–62. June 2005. doi:10.1038/sj.embor.7400428. PMID 15891766.
- ↑ "The complete genome sequence of Escherichia coli K-12". Science 277 (5331): 1453–62. September 1997. doi:10.1126/science.277.5331.1453. PMID 9278503.
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