Biology:SCAMP2
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Secretory carrier-associated membrane protein 2 is a protein that in humans is encoded by the SCAMP2 gene.[1][2]
This gene product belongs to the SCAMP family of proteins which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that the SCAMPs may function at the same site during vesicular transport rather than in separate pathways.[2]
References
- ↑ "Three mammalian SCAMPs (secretory carrier membrane proteins) are highly related products of distinct genes having similar subcellular distributions". J Cell Sci 110 (17): 2099–107. Nov 1997. doi:10.1242/jcs.110.17.2099. PMID 9378760.
- ↑ 2.0 2.1 "Entrez Gene: SCAMP2 secretory carrier membrane protein 2". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10066.
Further reading
- "Evidence for colocalization and interaction between 37 and 39 kDa isoforms of secretory carrier membrane proteins (SCAMPs)". J. Cell Sci. 110 (13): 1533–41. 1997. doi:10.1242/jcs.110.13.1533. PMID 9224770.
- "Perturbation of a very late step of regulated exocytosis by a secretory carrier membrane protein (SCAMP2)-derived peptide". J. Biol. Chem. 277 (38): 35357–63. 2002. doi:10.1074/jbc.M202259200. PMID 12124380.
- "Role of Secretory Carrier Membrane Protein SCAMP2 in Granule Exocytosis". Mol. Biol. Cell 13 (12): 4266–78. 2003. doi:10.1091/mbc.E02-03-0136. PMID 12475951.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Secretory carrier membrane proteins interact and regulate trafficking of the organellar (Na+,K+)/H+ exchanger NHE7". J. Cell Sci. 118 (Pt 9): 1885–97. 2005. doi:10.1242/jcs.02315. PMID 15840657.
- "A human protein-protein interaction network: a resource for annotating the proteome". Cell 122 (6): 957–68. 2005. doi:10.1016/j.cell.2005.08.029. PMID 16169070.
- "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
- "Subcellular redistribution of the serotonin transporter by secretory carrier membrane protein 2". J. Biol. Chem. 281 (39): 28901–9. 2006. doi:10.1074/jbc.M602848200. PMID 16870614.
- "Secretory carrier membrane protein SCAMP2 and phosphatidylinositol 4,5-bisphosphate interactions in the regulation of dense core vesicle exocytosis". Biochemistry 46 (38): 10909–20. 2007. doi:10.1021/bi701121j. PMID 17713930.
External links
- SCAMP2 human gene location in the UCSC Genome Browser.
- SCAMP2 human gene details in the UCSC Genome Browser.
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