Biology:SFRS2

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Short description: Protein-coding gene in humans


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Splicing factor, arginine/serine-rich 2 is a protein that in humans is encoded by the SFRS2 gene.[1][2][3]

Interactions

SFRS2 has been shown to interact with CDC5L[4] and ASF/SF2.[5]

References

  1. "Chromosomal localization of mouse and human genes encoding the splicing factors ASF/SF2 (SFRS1) and SC-35 (SFRS2)". Genomics 29 (1): 70–9. September 1995. doi:10.1006/geno.1995.1216. PMID 8530103. 
  2. "Isolation of a complementary DNA that encodes the mammalian splicing factor SC35". Science 256 (5056): 535–8. April 1992. doi:10.1126/science.1373910. PMID 1373910. Bibcode1992Sci...256..535F. 
  3. "Entrez Gene: SFRS2 splicing factor, arginine/serine-rich 2". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6427. 
  4. "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". The EMBO Journal 19 (23): 6569–81. December 2000. doi:10.1093/emboj/19.23.6569. PMID 11101529. 
  5. "Functional properties of p54, a novel SR protein active in constitutive and alternative splicing". Molecular and Cellular Biology 16 (10): 5400–8. October 1996. doi:10.1128/MCB.16.10.5400. PMID 8816452. 

Further reading

External links

  • Overview of all the structural information available in the PDB for UniProt: Q01130 (Serine/arginine-rich splicing factor 2) at the PDBe-KB.